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Jack saved an article
168d ago
Get your work recognized: write a brag document
Get your work recognized: write a brag document
Julia Evans • jvns.ca
Jackson saved an email
168d ago
a digital career path for curious people
But not just any second-brain app. One that is actually useful.
Dan Koe • email
Jack highlighted 4 parts of an article
172d ago
“Elizabeth shares that Neura acquired their first 500 patients off of Facebook after doing a lot of user research up front with a high volume group.”
“Neura’s focus isn’t to change the healthcare decisions made by clinicians but to make them more accessible to patients, so working with doctors is essential to their mission.”
“How are they perceiving it as different than their status quo experience?”
“Ask yourself:
Lessons From Elizabeth Burstein, Neura Health: Closing the Access and Quality Gap in Neurological Care • Vivien Ho
Jack saved an article
172d ago
Lessons from Elizabeth Burstein, Neura Health: Closing the access and quality gap in neurological care
Neura Health is a virtual neurology clinic with a mission to improve the access and quality of neurological care.
Vivien Ho • medium.com
Jack highlighted 1 part of a book
172d ago
“Repeated one hundred times, everything (including guilt) disintegrates into meaningless syllables.”
Time Shelter • Georgi Gospodinov and Angela Rodel
Jack saved an article
174d ago
Hackers and Painters
When I finished grad school in computer science I went to art school to study painting. A lot of people seemed surprised that someone interested in computers would also be interested in painting.
Paul Graham • www.paulgraham.com
Jack saved an article
175d ago
Patient Portal
These are all helpful notes I have received recently from the Boston-centered medical behemoth that provides my care. Lately, I have been fantasizing about one more message I would like to get.
New England Journal of Medicine • ai.nejm.org
Jack highlighted 1 part of a book
175d ago
“After a dictatorship of the future, as my friend K. would say, came the dictatorship of the past.”
Time Shelter • Georgi Gospodinov and Angela Rodel
Jackson saved a RSS feed item
176d ago
Lost on purpose
…of course, if you’re lost on purpose, you’re not lost. Lost is only possible if you are fixed on getting somewhere specific.
Seth Godin • seths.blog
Jack highlighted 2 parts of a book
176d ago
“Their arguments range from free medical care to the”
“I no longer remember who said that a nation was a group of people who have agreed to jointly remember and forget the same things.”
Time Shelter • Georgi Gospodinov and Angela Rodel
Jackson saved a RSS feed item
176d ago
Weekly Dose of Optimism #74
Solar Surge, Nuclear Hermes, Self-Driving Labs, CAR-T, Retro Biosciences, AOM Season 1 Finale
Daniel McCormick • www.notboring.co
Jackson saved a RSS feed item
177d ago
x1000
The future creeps up on us slowly. But when it leaps dramatically, we notice. One spam phone call a day is an irritation. 1,000 of them destroy the utility of the phone. One photographer undercutting our rates is a threat. 1,000 of them means we can’t make a living at it any longer. We’re facing […]
Seth Godin • seths.blog
Jack saved an article
177d ago
The Age Gappers
They say they’re happy. Why is it so hard to believe them?
Lila Shapiro • www.thecut.com
Jack highlighted 1 part of a book
178d ago
“How can we gain a little more time for tomorrow, when we face a critical deficit of future?”
Time Shelter • Georgi Gospodinov and Angela Rodel
Jackson saved a RSS feed item
179d ago
Momentum, Consolidation, and Breakout
Lessons from 2023, the year the momentum stalled
Packy McCormick • www.notboring.co
Jackson saved a RSS feed item
180d ago
The problems with flat out
The desire for 11 is proof that we often want to go all the way to ten. While 11 is silly, there is a lot of pressure to give our all. But there are problems. The first is that if you try to sprint an entire marathon, you’ll hurt yourself. Systems can be stressed for […]
Seth Godin • seths.blog
Jack highlighted 1 part of a book
181d ago
“If you discover traces of another time, it will be during some unremarkable afternoon. An afternoon during which nothing in particular has happened, except for life itself … who said that?”
Time Shelter • Georgi Gospodinov and Angela Rodel
Jackson saved an email
182d ago
the future of work is play
If every action is toward a conscious or unconscious goal, it seemed like everyone was eager to be overweight, unhealthy, overworked, and broke.
Dan Koe • email
Jackson saved a RSS feed item
183d ago
The friendly professional
Friendly doesn’t mean saying ‘yes’ all the time, or changing every policy, or giving up our principles. Friendly is how it feels, not what it does.
Seth Godin • seths.blog
Jackson saved a RSS feed item
184d ago
Weekly Dose of #73
Nuclear AI, Approved CRISPR, Diabetes Implants, Morning Sickness, MDMA Application, FunSearch
Daniel McCormick • www.notboring.co
Jackson saved a RSS feed item
184d ago
Signal and noise
If the signal is very weak and the noise is large, it’s easy to imagine that there’s no signal at all. AI and computers can be used as lenses now, which means we can strip away the noise and see things that we certainly didn’t expect. Dina Katabi at MIT can point a radio antenna […]
Seth Godin • seths.blog
Jackson saved a RSS feed item
184d ago
LayerZero: The Language of the Omnnichain
A Deep Dive on the TCP/IP for Blockchains
Packy McCormick • www.notboring.co
Jack highlighted 1 part of a book
185d ago
“Suddenly the ads have become the true news about that time.”
Time Shelter • Georgi Gospodinov and Angela Rodel
Jackson saved a RSS feed item
185d ago
Eight marketing maxims
Seth Godin • seths.blog
Jack saved an article
186d ago
The anatomy of shadcn/ui
If you were roaming around in the JavaScript ecosystem this year you might have come across this interesting UI library called shadcn/ui.
manupa.dev • manupa.dev
Jack highlighted 2 parts of a book
188d ago
“To be merciless toward the past. Because the past itself is merciless. That obsolete organ, like some appendix, which otherwise would become inflamed, it would throb and ache. If you can survive without it, better to cut”
“Only a diary could bring together the personal and the historical like that.”
Time Shelter • Georgi Gospodinov and Angela Rodel
Jackson saved a RSS feed item
188d ago
Elegant and classy
If you announce that something is elegant or classy, it probably isn’t. There’s a humility to hospitality and sophistication that evaporates when we name it.
Seth Godin • seths.blog
Jackson saved an email
189d ago
you won't be the same in 6 months
Most people, even though they don’t know it, are asleep.
Dan Koe • email
Jackson saved a RSS feed item
191d ago
Weekly Dose of Optimism #72
Gemini, Qubits, Brain Implants, saRNA, Biotech on Mars, Age of Miracles
Daniel McCormick • www.notboring.co
Jackson saved a RSS feed item
193d ago
The Morality of Having Kids in a Magical, Maybe Simulated World
Why the Climate Crisis May Be Proof We're In a Simulation
Packy McCormick • www.notboring.co
Jackson saved a RSS feed item
193d ago
Hope and expectations
They’re not the same thing. Hope can fuel us. Hope can be refilled. Hope opens the door to possibility. Expectations, on the other hand, are a trap. They make us brittle and lead to disappointment. When we raise our hopes and lower our expectations, we establish a resilient way forward.
Seth Godin • seths.blog
Jack saved an article
193d ago
At least five interesting things for the middle of your week (#21)
Saudi oil, delayed economic optimism, the EV revolution, U.S. education performance, Indian industrialization, and Chinese urbanism
Noah Smith • www.noahpinion.blog
Jackson saved an email
196d ago
the anti-niche
The government and culture influence the school system. The school system creates resources for students to learn from.
Dan Koe • email
Jackson saved a RSS feed item
198d ago
Weekly Dose of Optimism #71
GLP-1s, Loyal, Material Discovery, Fervo,AI Optimism, Energy
Daniel McCormick • www.notboring.co
Jackson saved a RSS feed item
200d ago
Narrative Tug-of-War
How to read EA v. e/acc
Packy McCormick • www.notboring.co
Jackson saved an email
200d ago
sorry about that (cyber monday ended early)
P. S.
Dan Koe • email
Jackson saved a RSS feed item
201d ago
Study groups
If I had to choose one metric that would determine how well someone would do in law school, it wouldn’t be the LSAT or another test. It would be whether or not they formed a study group, and who else was in it. Of course, the same is true for your project, or any sort […]
Seth Godin • seths.blog
Jackson saved an email
201d ago
last call cyber monday
Last chance to take advantage of me and get up to 50% off my writing and business products. Grab the deals here.
Dan Koe • email
Jackson saved an email
201d ago
omg it's *cyber monday*
I have a lot of plans with the book, software, and one final product next year - so it wouldn't make sense to discount them again.
Dan Koe • email
Jackson saved a RSS feed item
203d ago
The long-range forecast keeps shifting
Exactly. That’s why it’s a forecast, not an accurate account of what’s going to happen in the future. This seems axiomatic, but our desire for certainty keeps letting us down. The shifting of forecasts is evidence that they’re merely forecasts.
Seth Godin • seths.blog
Jackson saved a RSS feed item
204d ago
After the meteorite
When it slams into your house and destroys it, we’re likely to pursue one of two lines of thinking: –How did I cause this? What choices did I make, what mistakes did I permit, why did I deserve to have this damage, or who can I blame? –Well, that happened, now what should I do? […]
Seth Godin • seths.blog
Jack saved an article
204d ago
How to scale a health tech business to $100 million ARR and beyond
Read our definitive benchmarks on over 100 venture-backed healthcare companies.
Sofia Guerra and Steve Kraus • www.bvp.com
Jackson saved a note
204d ago
note
Jackson highlighted 1 part of an article
204d ago
“It’s easy to imagine that Resistance is for screenwriters or novelists. Writer’s block and procrastination. But anyone leading a project of any kind–a business, a non-profit, a campaign–confronts it as well.”
Seth's Blog : Project Resistance • seths.blog
Jackson saved an email
204d ago
fine, i'll conform, well done
So - just like everyone else is saying - this is the lowest price you will be able to get my products.
Dan Koe • email
Jackson saved a RSS feed item
205d ago
Weekly Dose of Optimism #70
Ceasefire, Q*, Deep learning Cancer Detection, Warp Speed Learnings, Nuclear Wins, Starship Separation
Daniel McCormick • www.notboring.co
Jack saved an article
205d ago
A builder’s guide to picking the right EHR
How to evaluate EHR vendors for your digital health product when no perfect solution exists.
lightmatter.com • www.lightmatter.com
Jack highlighted 1 part of an article
205d ago
“I shifted my focus from satisfying customers to delighting them.”
How to Define Your Product Strategy | by Gibson Biddle | Medium • gibsonbiddle.medium.com
Jack saved an article
205d ago
How to Define Your Product Strategy
A step-by-step guide to creating a product strategy for your company.
Gibson Biddle • gibsonbiddle.medium.com
Jack saved an article
206d ago
#3 The Strategy/Metric/Tactic Lockup
How to assign metrics and tactics to each high-level hypothesis.
Gibson Biddle • medium.com
Jack highlighted 1 part of an article
206d ago
“Given the need for ongoing business model experiments, there was non-stop price and plan testing. Today, prices range from nine to sixteen dollars (US).”
#2 From DHM to Product Strategy • Gibson Biddle
Jack saved an article
206d ago
#2 From DHM to Product Strategy
You have ideas to delight customers, to build hard to copy advantage and experiment with your business model. Now what?
Gibson Biddle • gibsonbiddle.medium.com
Jack saved an article
206d ago
#7 The Product Roadmap
A roadmap is an expression of your strategy. It shows how projects fit together, along with a rough time estimate
Gibson Biddle • gibsonbiddle.medium.com
Jackson saved a RSS feed item
206d ago
OpenAI & Grand Strategy
Altman, Augustus, and Preparing for Tech's Coming Battles
Packy McCormick • www.notboring.co
Jackson saved a RSS feed item
207d ago
Long form AI
The new version of Claude can read a document of up to 400 pages in about three minutes. You can then ask it for criticism, summaries or other insights. I wouldn’t use it on a piece of literature, but if you’re reading for work (aren’t we all), it will dramatically increase how much you can […]
Seth Godin • seths.blog
Jackson saved a RSS feed item
210d ago
The perfect conditions
Somewhere, there is the ideal soil for growing mangoes. Or the best possible wave for surfing. Or the most romantic sunset for a proposal. But it’s not right here and it’s not right now. Our success has a lot to do with how we dance with conditions that aren’t quite perfect.
Seth Godin • seths.blog
Jackson saved an email
210d ago
make millions with your mind
One other thing before we start – we have opened up more spots for VIP and Mastermind.
Dan Koe • email
Jack highlighted 3 parts of an article
211d ago
“Can law enforcement use your agent as evidence against you?”
“And you’re scored not only on how accurate you are but also on how calibrated your confidence is. So, in an ideal case, you were very confident about the predictions you were right about, and you had wide confidence intervals, a lot of uncertainty, about the predictions you were wrong about”
“The single strongest predictor, three times more powerful than cognitive ability or IQ, is how often they rethink their forecasts”
Anti-Patterns of 10x Thinking • nfx.com
Jackson saved a RSS feed item
212d ago
Weekly Dose of Optimism #69
CRISPR, Batkid, GraphCast, Nuclear Pledge, Starship, AoM5
Daniel McCormick • www.notboring.co
Jack saved an email
212d ago
Fwd: Does Anaesthesia Prove Ketamine Placebo?
Ketamine is a dissociative drug - it produces weird drug effects like feelings of bodylessness and ego death. Recent research suggests it’s a powerful antidepressant.
Jack Weatherilt • email
Jack saved an article
212d ago
The End of Organizing
How GPT-3 will turn your notes into an *actual* second brain
Dan Shipper • every.to
Jackson saved a RSS feed item
213d ago
Blockchains As Platforms
Benefits, Drawbacks, and Trade-Offs
Packy McCormick • www.notboring.co
Jackson saved an article
214d ago
Deception Point
Crime & Thrillers · 2009
Dan Brown • books.apple.com
Jackson saved a RSS feed item
215d ago
A long time is not the same as never
It might feel like an endless slog now, but when the innovation appears, people won’t remember how long it took to get here. Often, we assume that today’s snapshot is actually the entire movie, but it rarely is.
Seth Godin • seths.blog
Jack highlighted 4 parts of an article
215d ago
“Unfortunately, the chemical imbalance explanation may have encouraged long term use of SSRIs because it falsely implies a serotonin deficiency needing long term replacement, perhaps for life. This false belief was identified in 10 qualitative studies of barriers and facilitators to discontinuing antidepressants when appropriate. SSRIs may cause side effects, including gastrointestinal bleeding and sexual dysfunction. Long term use of antidepressants may make it more difficult to come off treatment and is associated with an increased risk of serious adverse events in older adults. Therefore we should not tell people with depression that antidepressants correct an imbalance or deficiency of serotonin, or that they will necessarily need long term treatment”
“people with more severe depression are given a combination of antidepressant and psychological treatment”
“The most exciting impact of AI agents is the way they will democratize services that today are too expensive for most people. They’ll have an especially big influence in four areas: health care, education, productivity, and entertainment and shopping.”
“If a tutoring agent knows that a kid likes Minecraft and Taylor Swift, it will use Minecraft to teach them about calculating the volume and area of shapes, and Taylor’s lyrics to teach them about storytelling and rhyme schemes”
AI Is About to Completely Change How You Use Computers • Gates Notes
Jack highlighted 1 part of an article
215d ago
“risks undermining the evidence based treatment of depression”
Antidepressants and the Serotonin Hypothesis of Depression • Tony Kendrick
Jackson saved a RSS feed item
216d ago
The reluctant spammer
“I don’t want to send this pitch to a list of every single podcaster in the world, but we have to get the word out.” “I don’t want to send an email to every one of our previous donors every three days until they unsubscribe, but our work is so important, it has to be […]
Seth Godin • seths.blog
Jack saved an article
216d ago
The OpenAI Keynote
OpenAI’s developer keynote was exciting, both because AI was exciting, and because OpenAI has the potential to be a meaningful consumer tech company.
Ben Thompson • stratechery.com
Jack saved an article
216d ago
Making architecture easy
Unlike nearly all other arts, architecture is inherently public and shared. That means that buildings should be designed to be agreeable – easy to like – not to be unpopular works of genius.
worksinprogress.co • worksinprogress.co
Jack saved an article
216d ago
The amateur presenter
Not “amateur” as in the unprepared professional. Amateur as in the passionate individual, untrained but with something to say. If you’re called on to give a talk or presentation, …
Seth's Blog • seths.blog
Jack saved an article
216d ago
Introduction
Books in Progress is what we call a “public drafting tool”: Drafts will be made available for comment from the public, allowing for direct collaboration between author and reader.
worksinprogress.co • books.worksinprogress.co
Jackson saved an email
217d ago
the daily routine that changed my life
The optimal state of inner experience is one in which there is order in consciousness.
Dan Koe • email
Jack saved an article
217d ago
AI-powered agents are the future of computing | Bill Gates
In 5 years, agents will be able to give health care advice, tutor students, do your shopping, help workers be far more productive, and much more
Bill Gates • www.gatesnotes.com
Jackson saved a RSS feed item
218d ago
Heavy Lemon Tuna
It’s easy to smirk at the ridiculous images one can make in twenty seconds with AI. People used to smirk at photographs in the 1800s. “I’ll believe it when I see it,” is no longer a useful thing to say. Truth is real, photos are not.
Seth Godin • seths.blog
Jackson saved a RSS feed item
219d ago
Weekly Dose of Optimism #68
devday, DACs, Zepbound, Turmeric, Humane, AoM e4
Daniel McCormick • www.notboring.co
Jack highlighted 3 parts of an article
219d ago
“A hyperbolic taper means that , particularly near the lowest doses. This is because (see the dose-occupancy graph below for fluoxetine). As the graph shows, dropping from 40 mg to 20 mg will not make much of a difference in terms of the drug’s effect. However, dropping from 5 mg to 2.5 mg means going from around 65% occupancy to 40% occupancy, a significant shift in the brain’s serotonin system. Going from 2.5 mg to a complete stop is an even sharper drop in serotonin occupancy: dropping from 40% to 0. Thus, as the dose approaches zero, smaller and smaller incremental changes may be necessary to give the brain time to adapt.”
“”
“antidepressant pills don’t come in an easily reduced form, which leads patients to try to cut them and break them into small enough doses—which doesn’t lead to very precise dosing. One solution to this issue is tapering strips, which have been used in the Netherlands recently. A patient can order a set of personalized tapering strips from one particular pharmacy in the Netherlands, which contains antidepressant medication packaged in the doses required for hyperbolic tapering.”
Hyperbolic Tapering Off Antidepressants Limits Withdrawal • Peter Simons
Jack saved an article
219d ago
Hyperbolic Tapering off Antidepressants Limits Withdrawal
New research by Jim van Os and Peter Groot finds that using hyperbolic tapering to discontinue antidepressants reduces withdrawal effects.
Peter Simons • www.madinamerica.com
Jackson saved an email
220d ago
4 hours left
Dan Koe • email
Jackson saved an email
220d ago
tonight is the night
If you want to find meaning, reinvent yourself, and create your ideal future: The Art Of Focus (my book) Keepsake Edition price increases tonight.
Dan Koe • email
Jackson saved a RSS feed item
221d ago
Tech is Going to Get Much Bigger
What happens when energy, intelligence, and labor get cheap?
Packy McCormick • www.notboring.co
Jackson saved an email
221d ago
the last one until next year
The book is a practical yet philosophical guide to find meaning, reinvent yourself, and create your ideal future by forging your own path with modern technology.
Dan Koe • email
Jack saved an article
222d ago
the anti depressant era
The introduction of sertraline in 1992 and paroxetine in 1993 led aggregate SSRI use to increase to 46% of depression patients by 1993.
The antidepressant era. • www.google.com
Jackson saved a RSS feed item
224d ago
Patience
It’s worth the most when it’s the most difficult to find.
Seth Godin • seths.blog
Jackson saved an email
224d ago
making money is spiritual
They get locked into what they think is a “higher” perspective that demonizes the sleazy salesman. In reality, this is an illusion.
Dan Koe • email
Jackson saved a RSS feed item
226d ago
Weekly Dose of Optimism
Mini Lasers, Giant Reactors, DNA Origami, AoM e3, AI EO, Palmer
Daniel McCormick • www.notboring.co
Jack saved an article
226d ago
Anti-Patterns of 10x Thinking
Pete Flint and Adam Grant discuss Adam's new book, Think Again, about the counterintuitive and competitive advantages of rethinking.
Pete Flint • www.nfx.com
Jack highlighted 1 part of an article
226d ago
“One good prompt I like to use: look at what students and engineers are doing. These have been the leading archetypes of early adopters in the past because they have very dense social networks with a high propensity to discover, adopt, and disseminate new technology.”
Reinventing Existing vs. Creating New Markets • Pete Flint
Jack saved an article
226d ago
Reinventing Existing vs. Creating New Markets
This essay helps Founders identify and anticipate the nuances between reinventing an existing market and creating a new one.
Pete Flint • www.nfx.com
Jackson saved a RSS feed item
228d ago
Two ways to defend the status quo
Neither is true, helpful or generous. Both happen all the time. Call it out when you see it.
Seth Godin • seths.blog
Jackson saved a RSS feed item
229d ago
Medicine's Endgame
The past, present, and future of cell-based therapy
Elliot Hershberg • www.notboring.co
Jack saved an article
229d ago
How to Make Yourself Into a Learning Machine
Shopify’s director of production engineering explains how reading broadly helps him get to the bottom of things
Dan Shipper • every.to
Jackson saved an email
229d ago
okay I made it not as expensive
But then I started figuring out how to coordinate an event, and I don't think having 2,000 people there for my first time would turn out well lol.
Dan Koe • email
Jackson saved a RSS feed item
230d ago
The 2 x 4 lessons
You’ll need two 8-foot boards and six five-gallon buckets. Each board is a standard 2 x 4, about two inches by four inches in size. And the bucket is about two feet deep. The first lesson is simple: Put the board on the floor and have a colleague walk from one end to the other. […]
Seth Godin • seths.blog
Jackson saved an email
231d ago
The Art Of Focus Official Book Summary
It's on Conscious Business and why those who think money is evil (usually the "higher" or more noble people) are usually the manipulative and evil ones.
Dan Koe • email
Jack saved an article
232d ago
How is the US economy managing to power ahead of Europe?
Economists predict transatlantic gap will continue to widen in the coming years
Financial Times • www.ft.com
Jackson saved a RSS feed item
233d ago
Age of Miracles
Launching Season 1: Nuclear Energy
Packy McCormick • www.notboring.co
Jack highlighted 3 parts of an article
237d ago
“Your capacity has a fixed upper bound, which is the number of hours in a day that you are able to work effectively. In a senior role, this may manifest as 3-4 hours in which you can dedicate to deep work such as writing, reading, or thinking. The rest of your time will be spent in meetings, 1:1s, and other activities that require your attention”
“Your capacity depletes when you are spending time on tasks that drain your energy”
“In order to better understand the relationship between your capacity and your energy levels, it is useful to keep a log of how you are spending your time and how you feel”
Manage Your Capacity, Not Your Time • James Stanier
Jack saved an article
237d ago
Time Management
We never have enough time. So we need to make the most of what we have. Managing it like an investment portfolio can help.
boz.com • boz.com
Jack saved an article
241d ago
Manage Your Capacity, Not Your Time
We obsess over managing our time. However, we should focus on managing our capacity instead: it's our ability to do our best work.
James Stanier • theengineeringmanager.substack.com
Jack saved an article
241d ago
She Sacrificed Her Youth to Get the Tech Bros to Grow Up
As a young industrial designer, Patricia Moore undertook a radical experiment in aging. Her discoveries reshaped the built world.
Lexi Pandell • www.wired.com
Jack highlighted 1 part of an article
256d ago
“'SubSpotlight': Subscribers aren't just numbers; they're people, sometimes with incredible stories, vast resources, and sparkling influence. Discover your VIPs among your subscriber base and engage with them. Out of my 70k subscribers, I found billionaires and childhood heroes! I would pay to find and connect with these VIPs, wouldn't you? Also, say hi to me if you’re reading this my VIPs”
Fwd: 11 Juicy Startup Ideas That You Should Totally Take • Jack Weatherilt
Jack saved an article
256d ago
Underrated ideas in psychology
How to build a barn door
Adam Mastroianni • www.experimental-history.com
Jack highlighted 4 parts of an article
256d ago
“So Hasok Chang talks about epistemic iteration, which is the idea that you make really bad model measurements. And then they inform you about a really bad theory, which helps you improve really bad measures. Then you go back and forth between theory and measurement. I like the example of glasses. He says, well, even with really bad glasses, you can see the world in some shape or form, which can help you make better glasses”
“I'm describing these studies in terms—as in, people doing things. The authors described these results as “inauthenticity causes feelings of impurity” and “dishonesty leads to creativity” and “signing makes ethics salient.” See what a difference it makes to talk about people and the things they did”
“Apparently is possible to reach the stratosphere of scientific achievement, to publish over and over again in “high impact” journals, to rack up tens of thousands of citations, and for none of it to matter”
“So if you hear that 60% of papers in your field don’t replicate, shouldn't you care a lot about which ones”
I’m So Sorry for Psychology’s Loss, Whatever It Is • experimental-history.com
Jack highlighted 4 parts of an article
256d ago
“There's a quite famous paper from 2016 where they followed a single participant for over a year every day. It's an open data set. It's quite remarkable. And this person tapered their
antidepressants—I think they're a researcher themselves. And they reached out to folks in the Netherlands and said, “Hey, do you want to study me while I taper my
antidepressants?” So what they did is they tapered the antidepressant blindly, meaning they didn't tell the person when exactly they switched out the antidepressant for a placebo. And unfortunately this person on day 200 or something pretty drastically relapses into depression. If you look at the mean severity score, the person has low variability in symptoms, and all of a sudden they go back into severe depression, and you don't pick this up based on the symptom scores before the transition.”
“When I talk to journalists about the warranty system we're building, I always say that measuring wind is probably a bad early warning sign for a thunderstorm or a hurricane, because when the wind starts, it's probably too late already. In the same way, measuring symptoms is probably a bad early warning for depression because when the symptoms start, you're probably already in the onset phase of depression. So they cannot forecast based on the severity of symptoms or the symptoms at the mean level, but based on the autocorrelations of the symptom relations or the affect relations over time.”
“The other is that accurate prediction can work without understanding. I always use the tides as an example. We understood the regularity of the tides. We could predict the tides really well, centuries, probably thousands of years before we had any understanding about the mechanisms governing the tides, right”
“The easiest to answer in our study, so we're collecting this data for five years, and everything will be open in the end that we are allowed to share.”
Fwd: Can AI and ML Predict Depression? • Jack Weatherilt
Jack highlighted 2 parts of an article
256d ago
“This work argues that it actually doesn't matter too much what particular nodes you assess in your system, as long as all of these nodes tap into the dynamics of the system, because it is measuring the dynamics that give you information about the system and not necessarily all the rest.”
“You can have lower variation in sleep problems in two ways. Maybe you sleep well every night or you sleep badly every night, but the lack of variability translates into higher auto correlations or lower standard deviation over time. So the system becomes more predictable. And that might signal an upcoming transition”
Fwd: Can AI and ML Predict Depression? • Jack Weatherilt
Jack saved an article
256d ago
My Site
CV | PUBLICATIONS RESEARCH | TEACHING
weebly.com • robinaugh.weebly.com
Jack highlighted 4 parts of an article
256d ago
“Some founders are hesitant to let customers mix — and vent — freely, but the gains outweigh the risks. If customers are going to post something negative, it’s better that they do it in a context you control than on Twitter”
“I used to hate criticism of any sort and actively avoided it. Now I try to always listen to it with the assumption that it’s true, and then decide if I want to act on it or not”
“trying to sell snake oil feels awful.”
“I think mental health problems are emergent. So they come out of systems of things that interact with each other. And these things that interact with each other are complex systems, and the elements are biological, psychological, and social.”
Fwd: Can AI and ML Predict Depression? • Jack Weatherilt
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256d ago
The Cadence
How to Operate a SaaS Startup
David Sacks • sacks.substack.com
Jack highlighted 4 parts of an article
256d ago
“9. Nurture your community.”
“Many founders are like bad politicians — they are “policy wonks.” They just want to talk about their features. I’ve got news for you: Nobody cares about your features. At least not yet. First people need to understand the problem you’re solving. Then they need to understand your solution. Only then will they be interested in your features.”
“Inevitably, as your startup becomes more successful, it will attract competitors. Don’t fall into the trap of seeing copycats as the enemy. Treat them as validation that the world is moving to your point of view”
“if you create the category, or define or redefine it, people will naturally look to you as the leader of it. This is particularly important in enterprise software. The modern version of the old saying that “nobody ever got fired for buying IBM” is that “nobody ever got fired for buying the category leader.””
Your Startup Is a Movement • David Sacks
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257d ago
EE380 Talk
I was asked at short notice to fill in for a speaker in Stanford's EE380 course who had to cancel. Below the fold is a hastily updated vers...
David. • blog.dshr.org
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257d ago
Biotech for the Biocurious
A field guide for the great biological century (with Shak Lakhani)
Will Manidis • minutes.substack.com
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258d ago
Your Startup Is a Movement
How Founders Should Think About Marketing
David Sacks • sacks.substack.com